HOW FREE RADICALS HARM OUR BODY & HOW TO GET RID OF IT!

๐—›๐—ฎ๐˜ƒ๐—ฒ ๐˜†๐—ผ๐˜‚ ๐—ฒ๐˜ƒ๐—ฒ๐—ฟ ๐˜„๐—ผ๐—ป๐—ฑ๐—ฒ๐—ฟ๐—ฒ๐—ฑ ๐—ต๐—ผ๐˜„ ๐—ณ๐—ฟ๐—ฒ๐—ฒ ๐—ฟ๐—ฎ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น๐˜€ ๐—ฎ๐—ฟ๐—ฒ ๐—บ๐—ฎ๐—ฑ๐—ฒ ๐—ถ๐—ป๐˜€๐—ถ๐—ฑ๐—ฒ ๐—ผ๐˜‚๐—ฟ ๐—ฏ๐—ผ๐—ฑ๐˜†?

Is it something harmful or useful?

๐—ฌ๐—˜๐—ฆ. ๐—ช๐—ฒ ๐—ป๐—ฒ๐—ฒ๐—ฑ ๐—ณ๐—ฟ๐—ฒ๐—ฒ ๐—ฟ๐—ฎ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น๐˜€ ๐—ถ๐—ป๐˜€๐—ถ๐—ฑ๐—ฒ ๐—ผ๐˜‚๐—ฟ ๐—ฏ๐—ผ๐—ฑ๐˜† ๐—ถ๐—ป ๐—ฐ๐—ฒ๐—ฟ๐˜๐—ฎ๐—ถ๐—ป ๐˜๐—ถ๐—บ๐—ฒ๐˜€.ย 

โœ“ To protect the cells from threating foreign cells during an inflammation/injury.ย 

๐—•๐—จ๐—ง ๐˜„๐—ต๐˜† ๐—ถ๐˜ ๐—ถ๐˜€ ๐—ฐ๐—ผ๐—ป๐˜€๐—ถ๐—ฑ๐—ฒ๐—ฟ๐—ฒ๐—ฑ ๐—›๐—”๐—ฅ๐— ๐—™๐—จ๐—Ÿ?

First, letโ€™s see how they are made.ย 

When a molecule/ atom ๐—น๐—ผ๐˜€๐—ฒ๐˜€ its electron, it becomes unstable. This kind of molecules/atoms are called free radicals. They are ๐—ต๐—ถ๐—ด๐—ต๐—น๐˜† ๐—ฟ๐—ฒ๐—ฎ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ฎ๐—ป๐—ฑ ๐—ฐ๐—ฎ๐—ฝ๐—ฎ๐—ฏ๐—น๐—ฒ ๐—ผ๐—ณ ๐—ต๐—ฎ๐—ฟ๐—บ๐—ถ๐—ป๐—ด other molecules and atoms. To become stable, they attack other molecules and steal electrons. Then the molecule that got attacked become a free radical. This happens as a cascade, forming abundant free radicals inside the body, ultimately leading to an oxidative stress. Cells become weak, mutate or die as a circumstance of oxidative stress.ย 

Letโ€™s see what are the factors that accelerate the production of free radicals inside our body.

โœ“ ๐—˜๐˜…๐—ฝ๐—ผ๐˜€๐˜‚๐—ฟ๐—ฒ ๐˜๐—ผ ๐—จ๐—ฉ ๐—ฟ๐—ฎ๐—ฑ๐—ถ๐—ฎ๐˜๐—ถ๐—ผ๐—ป

โœ“ ๐—”๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ผ๐—ฟ ๐—ฝ๐—ฎ๐˜€๐˜€๐—ถ๐˜ƒ๐—ฒ ๐˜€๐—บ๐—ผ๐—ธ๐—ถ๐—ป๐—ด

โœ“ ๐—˜๐˜…๐—ฐ๐—ฒ๐˜€๐˜€๐—ถ๐˜ƒ๐—ฒ ๐—ฎ๐—น๐—ฐ๐—ผ๐—ต๐—ผ๐—น ๐—ฐ๐—ผ๐—ป๐˜€๐˜‚๐—บ๐—ฝ๐˜๐—ถ๐—ผ๐—ป

โœ“ ๐—˜๐˜…๐—ฝ๐—ผ๐˜€๐˜‚๐—ฟ๐—ฒ ๐˜๐—ผ ๐—ฒ๐—ป๐˜ƒ๐—ถ๐—ฟ๐—ผ๐—ป๐—บ๐—ฒ๐—ป๐˜๐—ฎ๐—น ๐—ฝ๐—ผ๐—น๐—น๐˜‚๐˜๐—ฎ๐—ป๐˜๐˜€

โœ“ ๐—ช๐—ฟ๐—ผ๐—ป๐—ด ๐—ฑ๐—ถ๐—ฒ๐˜๐—ฎ๐—ฟ๐˜† ๐—ฝ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ถ๐—ฐ๐—ฒ๐˜€ (๐—–๐—ผ๐—ป๐˜€๐˜‚๐—บ๐—ฝ๐˜๐—ถ๐—ผ๐—ป ๐—ผ๐—ณ ๐—บ๐—ฒ๐—ฎ๐—น๐˜€ ๐˜„๐—ถ๐˜๐—ต ๐—ต๐—ถ๐—ด๐—ต ๐—ณ๐—ฎ๐˜/๐˜€๐˜‚๐—ด๐—ฎ๐—ฟ)

โœ“ ๐—ง๐—ผ๐—ผ ๐—บ๐˜‚๐—ฐ๐—ต ๐—ฒ๐˜…๐—ฒ๐—ฟ๐—ฐ๐—ถ๐˜€๐—ฒ/ ๐—ฝ๐—ต๐˜†๐˜€๐—ถ๐—ฐ๐—ฎ๐—น ๐˜€๐˜๐—ฟ๐—ฒ๐˜€๐˜€ย 

Exposure to above factors can create free radicals inside your body.

Let’s see, how our body get affected by free radicals.

๐—ฆ๐—ธ๐—ถ๐—ป ๐—–๐—ฒ๐—น๐—น๐˜€

Fibers like collagen and elastin get damaged making mutate and dead cells. This contributes to the process of โ€œ๐—”๐—ด๐—ถ๐—ป๐—ดโ€ happens faster.ย 

๐—ก๐—ฒ๐—ฟ๐˜ƒ๐—ฒ ๐—–๐—ฒ๐—น๐—น๐˜€ย 

In extreme cases, ๐—ฐ๐—ฒ๐—น๐—น๐˜€ ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—ฏ๐—ฟ๐—ฎ๐—ถ๐—ป ๐—ฐ๐—ฎ๐—ป ๐—ด๐—ฒ๐˜ ๐—ฑ๐—ฎ๐—บ๐—ฎ๐—ด๐—ฒ๐—ฑ which can lead to neurodegenerative diseases like Alzheimerโ€™s disease.ย 

๐—•๐—น๐—ผ๐—ผ๐—ฑ ๐—ฉ๐—ฒ๐˜€๐˜€๐—ฒ๐—น๐˜€

Cells in the blood vessel membrane get damaged. To cover up the damage the Liver produces Low Density Lipoproteins (๐—Ÿ๐——๐—Ÿ) more than the body usually requires. When free radicals continue to damage cells, the frequency of ๐—Ÿ๐——๐—Ÿ production also goes up which finally results in having uncontrolled levels of total Cholesterol in blood. Increased production of ๐—Ÿ๐——๐—Ÿ can block the arteries that leads into many cardiovascular diseases.ย 

๐—ฆ๐—ข, ๐—ต๐—ผ๐˜„ ๐—ฐ๐—ฎ๐—ป ๐˜„๐—ฒ ๐—ด๐—ฒ๐˜ ๐—ฟ๐—ถ๐—ฑ ๐—ผ๐—ณ ๐˜๐—ต๐—ฒ๐˜€๐—ฒ ๐—™๐—ฅ๐—˜๐—˜ ๐—ฅ๐—”๐——๐—œ๐—–๐—”๐—Ÿ๐—ฆ?

The solution is consuming ๐—”๐—ป๐˜๐—ถ-๐—ผ๐˜…๐—ถ๐—ฑ๐—ฎ๐—ป๐˜๐˜€.

๐—”๐—ป๐˜๐—ถ-๐—ผ๐˜…๐—ถ๐—ฑ๐—ฎ๐—ป๐˜๐˜€ are present in many natural food sources such as vegetables, yams, grains and fruits. There is a variety of anti-oxidants including Carotenoids, Flavonoids, Vitamin C & E.

These anti-oxidants can donate electrons to free radicals, neutralizing them inside the body.ย 

Researches show that plants like: ๐—”๐—น๐—ผ๐—ฒ ๐˜ƒ๐—ฒ๐—ฟ๐—ฎ, ๐—ข๐—ป๐—ถ๐—ผ๐—ป, ๐—š๐—ฎ๐—ฟ๐—น๐—ถ๐—ฐ, ๐—–๐—ถ๐—ป๐—ป๐—ฎ๐—บ๐—ผ๐—ป, ๐—•๐—น๐—ฎ๐—ฐ๐—ธ ๐—–๐˜‚๐—บ๐—ถ๐—ป, ๐—–๐˜‚๐—ฟ๐—ฟ๐˜† ๐—Ÿ๐—ฒ๐—ฎ๐—ณ, ๐—™๐—ฒ๐—ป๐˜‚๐—ด๐—ฟ๐—ฒ๐—ฒ๐—ธ, ๐—ก๐—ฒ๐—ฒ๐—บ, ๐—š๐—ถ๐—ป๐—ด๐—ฒ๐—ฟ, ๐—ง๐˜‚๐—ฟ๐—บ๐—ฒ๐—ฟ๐—ถ๐—ฐ ..etc., contain various anti-oxidants.ย 

Fruits that are rich in anti-oxidants: ๐—ฃ๐—ฎ๐—ฝ๐—ฎ๐˜†๐—ฎ, ๐— ๐—ฎ๐—ป๐—ด๐—ผ, ๐—ง๐—ผ๐—บ๐—ฎ๐˜๐—ผ, ๐—˜๐—ด๐—ด ๐—™๐—ฟ๐˜‚๐—ถ๐˜, ๐— ๐—ฒ๐—น๐—ผ๐—ป, ๐—•๐—ฒ๐—ฟ๐—ฟ๐—ถ๐—ฒ๐˜€, ๐—Ÿ๐—ฒ๐—บ๐—ผ๐—ป๐˜€, ๐—š๐˜‚๐—ฎ๐˜ƒ๐—ฎ ๐—ฎ๐—ป๐—ฑ ๐—”๐˜ƒ๐—ผ๐—ฐ๐—ฎ๐—ฑ๐—ผ.ย 

๐‘บ๐’ ๐’๐’†๐’• ๐’–๐’” ๐’„๐’๐’๐’„๐’†๐’“๐’ ๐’•๐’‰๐’†๐’”๐’† ๐’‡๐’‚๐’„๐’•๐’” ๐’‚๐’๐’… ๐’„๐’‰๐’‚๐’๐’ˆ๐’† ๐’๐’–๐’“ ๐’๐’Š๐’‡๐’†๐’”๐’•๐’š๐’๐’†s ๐’•๐’ ๐’Ž๐’๐’“๐’† ๐’‰๐’†๐’‚๐’๐’•๐’‰๐’Š๐’†๐’“ ๐’๐’๐’†๐’”!

/By Anusha Abeywardana

(B.Sc. (Hons.) in Pharmacy

University of Colombo

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